Adult onset diabetes in twins
RESEARCH DESIGN AND METHODS
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The earliest evidence for a major genetic contribution to the development of type 2 diabetes came from classical experimental paradigms including twin, family.
31 Mar LBW is common among twins. It is unknown whether twin status per se is associated with risk of type 2 diabetes, and valid concordance rates of.
Description:Download powerpoint Figure 2 Insulin action after a meal. Insulin activates transport of glucose to muscle and adipose tissue, and also promotes synthesis of glycogen and triglycerides by the liver. Increased insulin levels inhibit glucose production by the liver, lipolysis in adipose tissue and proteolysis in muscle. They also inhibit ketogenesis by the liver. Although the brain uses glucose as its main energy source, it can also use ketone bodies when glucose levels are insufficient for example, during fasting. There are a number of glucose counter-regulatory hormones, such as glucagon, cortisol, epinephrine, and norepinephrine, which raise plasma glucose levels and therefore counteract hypoglycaemia.
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